FIG 1 .

Molecular-level view of the plant-based diet. (A) Food-disease association network for the 14 foods in the plant-based diet of this study. The general disease classes were colored differently as illustrated by the legend. The size of the food nodes reflects the number of disease connections for each food. (B) Gut microbiota-specific protein target space of the food phytochemicals. (Left) Human direct targets (red rectangles) of the food phytochemicals (green hexagons) were retrieved from the ChEMBL database. (Right) The microbiota-specific direct targets (red rectangles) and their protein-protein interaction (PPI) partners (blue rectangles) were derived after incorporating orthologous relationships with human and STRING protein-protein interaction data.