FIG 5 .

DC-autophagy contributes to immune infiltration into the cornea during HSK. atg5^fl/fl and atg5^fl/fl CD11c-cre female mice were challenged with 2 × 10⁶ PFU of HSV-1 (strain 17) unilaterally. Corneas were analyzed by flow cytometry at 14 dpi (A to F; n ≥ 7 per group) and 38 dpi (G to L; n ≥ 11 per group). Samples were first gated on CD45⁺ cells before gating on subpopulations. In each panel, quantification of each cell subset is presented as percentage (left) and total number (right) in the cornea. Cell populations analyzed include CD45⁺ immune cells (A and G), CD11b⁺ GR1⁺ neutrophils and macrophages (C and I), CD11b⁺ GR1⁻ myeloid cells (B and H), CD11c⁺ dendritic cells (D and J), CD4⁺ T cells (E and K), and CD8⁺ T cells (F and L). Statistical significance was determined by unpaired parametric t test. *, P < 0.05.