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Schematic illustration of the cell envelope of Mycobacterium tuberculosis and potential metabolite targets. Metabolites from the peptidoglycan layer (d-glucosamine and 2-acetylamino-2-deoxy-β-d-glucopyranose) can be used for mycobacterial infection diagnosis, and metabolites from the mycolic acid layer (2-deoxy-d-erythro-pentitol and methyl-17-methyloctadecanoic acid) can be used to differentiate mycobacterial species.
