Table 2.
Changes in the levels of DNA damage (tail length, % DNA in tail, tail moment and olive tail moment) in L929 mouse fibroblasts.
| Group | Dose (μg/mL) | Tailing Rate (%) (n = 200) | Tailing Cell (n = 20) | ||
|---|---|---|---|---|---|
| DNA in Tail (%) | Tail Length | Olive Tail Moment | |||
| negative control | — | 11.34 ± 2.17 | 4.67 ± 4.23 | 32.20 ± 20.18 | 7.27 ± 6.23 |
| positive control | — | 88.25 ± 5.45 a | 24.83 ± 20.17 a | 207.45 ± 84.69 a | 47.56 ± 23.66 a |
| 2.2 nm CdSe | 3.5 | 14.67 ± 3.68 | 6.33 ± 5.02 | 37.64 ± 25.42 | 9.16 ± 7.30 |
| 7 | 17.24 ± 5.58 | 13.53 ± 10.46 | 89.27 ± 40.15 | 20.43 ± 18.33 | |
| 14 | 25.55 ± 5.84 a | 24.00 ± 19.68 a | 138.35 ± 72.64 a | 28.78 ± 20.73 a | |
| 2.2 nm CdTe | 3.5 | 13.22 ± 4.78 | 5.67 ± 4.64 | 38.86 ± 29.95 | 11.41 ± 6.27 |
| 7 | 18.85 ± 5.97 | 14.00 ± 12.94 a | 78.80 ± 45.85 a | 22.28 ± 18.69 | |
| 14 | 24.73 ± 4.57 a | 26.67 ± 20.74 a | 123.55 ± 65.73 a | 27.58 ± 16.62 a | |
| 3.5 nm CdTe | 3.5 | 13.35 ± 3.67 | 5.07 ± 4.48 | 38.37 ± 26.84 | 9.81 ± 6.16 |
| 7 | 14.49 ± 4.83 a | 12.67 ± 9.43 | 59.27 ± 30.15 | 18.62 ± 12.99 | |
| 14 | 19.25 ± 4.14 a,b | 23.33 ± 20.27 a,b | 94.68 ± 63.86 a,b | 20.11 ± 16.30 | |
Values are given as mean ± S.D. of six experiments in each group. a p < 0.05 vs. control; b p < 0.05 vs. the same dose of 2.2 nm CdTe group.