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. 2015 Sep 8;43(19):9529–9540. doi: 10.1093/nar/gkv868

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© The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — CptI_Er is an H-Type pseudoknot with unique features in its L1 and L2 loop regions. (A) Left: a coloured schematic of CptI_Er showing its two stems (S1 and S2), and two loop regions (L1 and L2); right: a representation of the schematic on a cartoon of a single CptI_Er monomer. (B) A close-up of the L1 loop region, unique in its dissociation with the stems altogether. It instead stacks with the proximal end of the L2 loop. (C) Close-up cartoon representations of the L2 loop region (brown), which can be divided into two halves—L2a and L2b. Above: the upper half (L2a) is a unique counterclockwise A-minor twist; below: the lower half (L2b) is a clockwise A-minor twist, with the change in directionality mediated by the ‘kink’ nucleotide (U30, teal).