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. 2015 Oct 7;43(19):9327–9339. doi: 10.1093/nar/gkv908

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© Published by Oxford University Press on behalf of Nucleic Acids Research 2015. This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 5. — Integrated analysis of gene regulation and gene-specific CpG methylation, copy number alterations and differentially expressed miRNAs in ACC. Venn diagrams show the total number of genes that are regulated by each mechanism: gene-specific CpG methylation, copy number alterations and differentially expressed miRNAs in ACC versus adrenocortical adenoma (A) and ACC versus normal adrenal cortex (B). (C) The top molecular pathways that are altered by the three modes of gene expression regulation mechanisms.