Table 2. Top listed genes that had copy number variation in ACC.
| Gene | Gene symbol | Fold change | Cytogenic location | Copy number alteration | % of frequency |
|---|---|---|---|---|---|
| ACC tumor versus benign tumor | |||||
| Mucin-Like 1 | MUCL1 | 5.1313105 | 12q13.2 | Gain | 50 |
| Discs, large (Drosophila) homolog-associated protein 4 | DLGAP4 | 4.066083 | 20q11.23 | Gain | 50 |
| ACC tumor versus normal | |||||
| Mucin-Like 1 | MUCL1 | 6.0820823 | 12q13.2 | Gain | 50 |
| Translocase of inner mitochondrial membrane 8 homolog A | TIMM8A | 6.052325 | xq22.1 | Gain | 50 |
| ACC tumor versus benign tumor | |||||
| dystonin | DST | −4.543177 | 6p12.1 | Loss | −62.5 |
| G protein-coupled receptor 116 | GPR116 | −4.2464156 | 6p12.3 | Loss | −62.5 |
| Ferritin, heavy polypeptide 1 | FTH1 | −6.976058 | 11q12.3 | Loss | −50 |
| Eukaryotic translation initiation factor 3, subunit M | EIF3M | −6.6611166 | 11p13 | Loss | −50 |
| Aldehyde dehydrogenase 3 family, member A2 | ALDH3A2 | −5.379404 | 17p11.2 | Loss | −50 |
| Solute carrier family 47 (multidrug and toxin extrusion), member 1 | SLC47A1 | −4.1039605 | 17p11.2 | Loss | −50 |
| ACC tumor versus normal | |||||
| dystonin | DST | −5.070555 | 6p12.1 | Loss | −62.5 |
| CCAAT/enhancer binding protein (C/EBP), delta | CEBPD | −6.8873086 | 8q11.21 | Loss | −50 |
| G protein-coupled receptor 116 | GPR116 | −6.809791 | 6p12.3 | Loss | −50 |
| Aldehyde dehydrogenase 3 family, member A2 | ALDH3A2 | −6.7790155 | 17p11.2 | Loss | −50 |
| Zinc finger E-Box binding homeobox 2 | ZEB2 | −6.7785573 | 2q22.3 | Loss | −50 |
| RAB2A, member RAS oncogene family | RAB2A | −6.750401 | 8q12.1 | Loss | −50 |
The cytogenic location, fold change of gene expression with the percentage of copy number alteration for the top listed genes in each comparison was tabulated.