Table 1. Effects of skeletal muscle aging on morphometric amd shape descriptors of subsarcolemmal and intermyofibrillar mitochondria.
| SS | IMF | |||
|---|---|---|---|---|
| YA | Old | YA | Old | |
|
Longitudinal Orientation | ||||
| Area (μm2) | 0,23 ± 0,24 | 0,39 ± 0,29* | 0,09 ± 0,16 | 0,11± 0,15 |
| Perimeter (μm) | 1,76 ± 0,91 | 2,37 ± 1,07** | 1,02 ± 0,58 | 1,17 ± 0,78** |
| Circularity | 0,83 ± 0,11 | 0,80 ± 0,13 | 0,87 ± 0,08 | 0,83 ± 0,12* |
| Feret's Diameter (μm) | 0,66 ± 0,38 | 0,88 ± 0,42** | 0,37 ± 0,23 | 0,44 ± 0,33** |
| Aspect Ratio | 1,65 ± 0,66 | 1,67 ± 0,57 | 1,38 ± 0,48 | 1,63 ± 0,81** |
| Form Factor | 1,24 ± 0,24 | 1,29 ± 0,27 | 1,143 ± 0,16 | 1,22 ± 0,29** |
| N | 165 | 258 | 1027 | 1309 |
|
Transverse Orientation | ||||
| Area (μm2) | 0,34 ± 0,29 | 0,38 ± 0,34 | 0,24 ± 0,18 | 0,21 ± 0,18 |
| Perimeter (μm) | 2,05 ± 0,94 | 2,23 ± 1,12** | 1,85 ± 0,83 | 1,76 ± 0,78** |
| Circularity | 0,87 ± 0,09 | 0,85 ± 0,13 | 0,85 ± 0,14 | 0,81 ± 0,15 |
| Feret's Diameter (μm) | 0,75 ± 0,35 | 0,82 ± 0,44 | 0,67 ± 0,33 | 0,66 ± 0,30 |
| Aspect Ratio | 1,47 ± 0,44 | 1,59 ± 0,67 | 1,55 ± 0,75 | 1,79 ± 0,82** |
| Form Factor | 1,16 ± 0,15 | 1,23 ± 0,35 | 1,23 ± 0,39 | 1,31 ± 0,38** |
| N | 248 | 196 | 387 | 442 |
Mean ± SD. Data were obtained from 4 different animals in each group. Ordinary one –way ANOVA with Sidak's multiple comparison test. YA = young adult
*
p<0.05;
**
p<0.01 vs YA.