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. 2015 Apr 19;6(19):17054–17064. doi: 10.18632/oncotarget.3881

Table 2. Significantly down-regulated genes in monocytes from aged vs. young rats.

Gene Description Fold change p FDR
S1pr1 Sphingosine 1-phosphate receptor 1 0.03 3.20E-04 2.68E-02
Hbe1 Hemoglobin, epsilon 1 0.04 7.40E-04 4.72E-02
Slc4a1 Solute carrier organic anion transporter family member 4A1 0.05 1.70E-04 1.69E-02
Eraf Alpha hemoglobin stabilizing protein 0.08 5.50E-04 3.83E-02
IGKV Immunoglobulin kappa light chain V region 0.08 4.00E-05 6.79E-03
IGG2A Immunoglobulin gamma-2A chain C region 0.10 1.20E-04 1.38E-02
Ccr10 C-C chemokine receptor type 10 0.11 3.00E-05 6.05E-03
Zcchc14 Zinc finger, CCHC domain-containing protein 14 0.12 4.00E-05 6.53E-03
Mzb1 Marginal zone B and B1 cell-specific protein 0.14 2.00E-05 5.35E-03
Tnfrsf17 Tumor necrosis factor receptor superfamily member 17 0.14 1.00E-05 3.24E-03
IGLC2 Immunoglobulin lambda-2 chain C region 0.16 3.00E-05 6.19E-03
Cd79b B-cell antigen receptor complex-associated protein, beta chain 0.17 1.00E-05 4.64E-03
Pxdc1 PX domain-containing protein 1 0.17 5.00E-05 7.84E-03
Vpreb3 Pre-B lymphocyte protein 3 0.17 3.00E-05 5.99E-03
Olr686 Olfactory receptor Olr686 0.19 1.30E-04 1.43E-02
Itih4 Inter-alpha-trypsin inhibitor heavy chain family, member 4 0.20 8.00E-05 1.01E-02
Slc22a23 Solute carrier family 22 member 23 0.20 2.00E-05 5.55E-03
Derl3 Derlin-3 0.23 1.00E-05 4.56E-03
Rhbdl1 Rhomboid, veinlet-like protein 1 0.23 3.00E-05 6.33E-03
Ms4a1 Membrane-spanning 4-domains, subfamily A, member 1 0.23 1.40E-04 1.46E-02
Cd79a B-cell antigen receptor complex-associated protein, alpha chain 0.23 1.00E-04 1.20E-02
Eaf2 ELL-associated factor 2 0.24 1.80E-04 1.75E-02
Sspn Sarcospan 0.24 4.90E-04 3.55E-02
Pde6h Cone-like cGMP-phosphodiesterase 6 gamma subunit 0.24 2.90E-04 2.58E-02
Try10 Trypsin 10 precursor 0.25 2.10E-04 1.92E-02
Fcer2 IgE Fc receptor, low affinity II, alpha polypeptide isoform b 0.26 1.70E-04 1.72E-02
RT1-CE10 RT1 class I, locus CE10 0.28 8.00E-05 1.07E-02
Myf6 Myogenic factor 6 0.30 1.70E-04 1.72E-02
Gas6 Growth arrest-specific protein 6 0.30 1.40E-04 1.47E-02
Jakmip1 Janus kinase and microtubule-interacting protein 1 0.31 9.00E-05 1.13E-02
Pon1 Serum paraoxonase/arylesterase 1 0.32 6.90E-04 4.50E-02
Dgkg Diacylglycerol kinase, theta 0.32 4.50E-04 3.35E-02
Txndc5 Thioredoxin domain-containing protein 5, endoplasmic reticulum 0.33 4.00E-05 6.49E-03
RT1-CE3 RT1 class I, locus CE3 0.33 1.80E-04 1.75E-02
RT1-A2 RT1 class I, locus A2 0.33 3.90E-04 3.09E-02
Idh1 Isocitrate dehydrogenase [NADP], cytoplasmic 0.35 5.80E-04 3.98E-02
Ticam1 Toll-like receptor adaptor molecule 1 0.36 3.90E-04 3.09E-02
Hvcn1 Hydrogen voltage-gated channel 1 0.37 3.60E-04 2.95E-02
Sec11c Signal peptidase complex catalytic subunit SEC11C 0.37 6.00E-05 8.26E-03
Musk Muscle, skeletal, receptor tyrosine protein kinase 0.38 6.40E-04 4.26E-02
Dgka Diacylglycerol kinase, alpha 0.39 5.90E-04 4.02E-02
Nol4l Nucleolar protein 4-like 0.42 6.80E-04 4.45E-02
Mkrn1 Makorin ring finger protein 1 0.43 4.10E-04 3.20E-02
Pdia4 Protein disulfide isomerase-associated 4 0.43 4.30E-04 3.31E-02