Figure 8. PAPSS1 silencing sensitizes A549 cells to radiation, as well as platinum-based agents and topoisomerase I inhibitors.

Cells transfected with PAPSS1 or scramble siRNA were subjected to selected doses of radiation. Data were normalized to non-irradiated controls (mean ± SD; n = 3). The dose response curves from chemotherapeutic treatments are displayed as mean ± SEM and are representative of at least three independent experiments.