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. 2013 Aug 12;6(19):17314–17327. doi: 10.18632/oncotarget.1168

Table 1. GEP changes following HDAC inhibition in myeloma cells.

Probe ID Gene Fold change
APi HDACi Combination
210538_s_at BIRC3 3 49.17 23.51 110.62
202644_s_at A20 14.63 NS 16.64
201502_s_at IκBα 4.93 NS 6.55
221903_s_at CYLD 2.04 2.47 4.16

H929 cells were treated with tosedostat (CHR-2797) 1 μM (APi), CHR-3996 250 nM (HDACi), or a combination of both for 24 hours then analysed on a U133 Plus 2.0 Array (Affymetrix) and a supervised analysis performed with dCHIP comparing the groups of treated cells to untreated cells. All p values were less than 0.05. NS, no significant change.