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. 2015 May 11;6(19):17532–17542. doi: 10.18632/oncotarget.3947

Figure 4. The combination of CFZ and TRAIL augments killing of cancer cells (A) with enhanced activation of caspases (B).

Figure 4

A, The indicated cancer cell lines were treated with different concentrations of CFZ alone, TRAIL alone, and the combination of CFZ and TRAIL for 24 h and then subjected to estimation of cell number with the SRB assay. The data are means ± SDs of four replicate determinations. B, The indicated cell lines were treated with 50 nM CFZ alone, 25 ng/ml TRAIL alone or their combination for 24 h and then subjected to preparation of whole-cell protein lysates and subsequent Western blot analysis. CF, cleaved fragment.