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. 2015 May 8;6(19):17713–17724. doi: 10.18632/oncotarget.4034

Table 2. Pathway analysis of genes comprising each of the BLBC modules.

Module 0 – Stress pathways FDR
AP-1 transcription factor network(N) <1.00e-03
HTLV-I infection(K) <1.00E-03
ATF-2 transcription factor network(N) <1.00e-03
ErbB1 downstream signaling(N) <1.00e-03
Osteoclast differentiation(K) <1.00e-03
Module 1 - T cell
TCR signaling(R) <1.00e-03
Primary immunodeficiency(K) <1.00e-03
TCR signaling in naive CD4+ T cells(N) <1.00e-03
T cell receptor signaling pathway(K) 1.50E-03
Cell adhesion molecules (CAMs)(K) 3.20E-03
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R) 9.36E-03
Module 2 - B cell
Fcgamma receptor (FCGR) dependent phagocytosis(R) <1.00e-03
Complement cascade(R) <1.00e-03
Signaling by the B Cell Receptor (BCR)(R) <1.00e-03
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell(R) <1.00e-03
Module 4 - Integrin signalling
Integrin signalling pathway(P) <1.00e-03
Module 5 - GPCR signaling
GPCR ligand binding(R) 3.00E-03
GPCR downstream signaling(R) 3.48E-02
Module 6 – Apoptosis
Apoptosis(K) <1.00e-03
Natural killer cell mediated cytotoxicity(K) 1.00E-03
Apoptosis(R) 5.71E-04