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. 2015 Oct 30;15:470. doi: 10.1186/s12879-015-1162-y

Table 2.

Rates of all-cause pneumonia among healthy, at-risk, and high-risk adults

All-Cause Pneumonia
No. of Person-Years Age 18–49 Years Age 50–59 Years Age ≥60 Years
Age Age Age Rate Rate Ratiosa Rate Rate Ratiosa Rate Rate Ratiosa
18-49 Years 50-59 Years ≥60 Years per 100 K (95 % CI) per 100 K (95 % CI) per 100 K (95 % CI)
Risk Group
 Healthy 4,334,344 1,194,431 1,308,873 441 684 1,439
 At-Risk 1,197,718 648,276 1,575,635 975 2.2 (2.1, 2.4) 1,554 2.3 (2.2, 2.4) 3,547 2.5 (2.4, 2.5)
  Chronic heart disease 116,350 145,449 703,271 1,147 2.6 (2.5, 2.8) 1,780 2.6 (2.5, 2.7) 4,451 3.1 (3.0, 3.2)
  Chronic lung disease 579,980 238,260 466,695 1,088 2.5 (2.3, 2.6) 2,195 3.2 (3.1, 3.3) 5,246 3.6 (3.5, 3.7)
  Diabetes 97,028 165,443 643,437 1,115 2.5 (2.4, 2.7) 1,592 2.3 (2.2, 2.4) 3,736 2.6 (2.5, 2.7)
  Asthma 323,267 102,513 165,056 1,112 2.5 (2.4, 2.7) 2,314 3.4 (3.2, 3.5) 4,621 3.2 (3.1, 3.3)
  Alcoholism 33,593 25,488 27,142 1,578 3.6 (3.4, 3.8) 2,754 4.0 (3.9, 4.2) 5,626 3.9 (3.8, 4.0)
  Chronic liver disease 154,804 154,616 321,444 1,015 2.3 (2.2, 2.5) 1,419 2.1 (2.0, 2.2) 2,861 2.0 (1.9, 2.1)
  Smokers 38,316 22,141 19,819 1,133 2.6 (2.4, 2.7) 2,529 3.7 (3.6, 3.8) 5,535 3.8 (3.7, 3.9)
  Down's syndrome 2,926 451 139 2,016 4.6 (4.4, 4.8) 7,987 11.7 (11.4, 11.9) 11,471 8.0 (7.8, 8.1)
  Neuromuscular/seizure disorder 49,368 18,445 36,733 1,669 3.8 (3.6, 4.0) 2,483 3.6 (3.5, 3.8) 6,711 4.7 (4.6, 4.8)
  Short gestation/low birthweight 1,607 0 4 622 1.4 (1.3, 1.5) 0 0.0 (----) 0 00.0 (----)
  Rheumatoid 48,367 35,563 83,318 1,164 2.6 (2.5, 2.8) 1,696 2.5 (2.4, 2.6) 3,842 2.7 (2.6, 2.8)
   Rheumatoid arthritis 26,323 28,126 76,319 1,193 2.7 (2.6, 2.9) 1,582 2.3 (2.2, 2.4) 3,830 2.7 (2.6, 2.7)
   Lupus 1,624 794 1,028 2,402 5.5 (5.2, 5.7) 3,777 5.5 (5.3, 5.7) 5,640 3.9 (3.8, 4.0)
   Crohn's 21,202 7,128 6,633 990 2.2 (2.1, 2.4) 1,796 2.6 (2.5, 2.7) 3,317 2.3 (2.2, 2.4)
 High-Risk 181,558 132,436 630,789 1,411 3.2 (3.0, 3.4) 2,559 3.7 (3.6, 3.9) 5,852 4.1 (4.0, 4.2)
  Cochlear implant 719 542 2,787 1,669 3.8 (3.6, 4.0) 2,768 4.0 (3.9, 4.2) 4,629 3.2 (3.1, 3.3)
  Functional/anatomic asplenia 11,350 3,580 8,583 1,665 3.8 (3.6, 4.0) 4,134 6.0 (5.9, 6.2) 9,705 6.7 (6.6, 6.9)
  HIV 7,940 2,692 7,386 1,952 4.4 (4.2, 4.6) 2,192 3.2 (3.1, 3.3) 3,994 2.8 (2.7, 2.9)
  Chronic renal failure 38,170 36,522 266,953 1,776 4.0 (3.8, 4.2) 3,313 4.8 (4.7, 5.0) 8,114 5.6 (5.5, 5.8)
  Immunosuppressants 84,727 81,587 381,069 1,779 4.0 (3.9, 4.2) 2,787 4.1 (3.9, 4.2) 5,053 3.5 (3.4, 3.6)
   Malignant neoplasms 82,755 80,199 379,086 1,556 3.5 (3.4, 3.7) 2,557 3.7 (3.6, 3.9) 4,957 3.4 (3.4, 3.5)
   Solid organ transplantation 2,574 1,850 2,924 8,509 19.3 (18.9, 19.7) 12,056 17.6 (17.3, 17.9) 15,768 11.0 (10.8, 11.1)
  Congenital immunodeficiency 38,927 10,800 16,179 1,123 2.5 (2.4, 2.7) 2,935 4.3 (4.1, 4.4) 6,385 4.4 (4.3, 4.5)
  Diseases of white blood cells 9,468 5,779 13,734 1,986 4.5 (4.3, 4.7) 3,063 4.5 (4.3, 4.6) 6,407 4.5 (4.3, 4.6)

aRelative to healthy counterparts