Table II.
LC–MS-MS Analyses of Smokers' Oral Fluid Specimens Before and After Smoking Cannabis
| Time (h) | THC (ng/mL) | THCCOOH (ng/mL) | THC (ng/mL) | THCCOOH (ng/mL) | THC (ng/mL) | THCCOOH (ng/mL) | THC (ng/mL) | THCCOOH (ng/mL) | THC (ng/mL) | THCCOOH (ng/mL) | THC (ng/mL) | THCCOOH (ng/mL) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Session 1 | ||||||||||||
| Subject | S3 | S5 | S9 | S17 | S18 | S20 | ||||||
| −1 | 23 | 0.6 | 19 | 1.105 | 8.9 | 0.113 | 10 | 0.141 | 5.9 | 0.046 | 5.1 | 0.045 |
| 0.25 | 3512 | 1.381 | 434 | 2.303 | 904 | 0.457 | 220 | 0.065 | 102 | 0.056 | 645 | 0.171 |
| 0.5 | MS | MS | 275 | 3.349 | 243 | 0.458 | 128 | 0.062 | 47 | 0.069 | 226 | 0.13 |
| 1 | 961 | 3.212 | 164 | 3.754 | 44 | 0.213 | 51 | 0.061 | 40 | 0.09 | 77 | 0.2 |
| 1.5 | 655 | 3.323 | 112 | 2.493 | 48 | 0.162 | 34 | 0.065 | 11 | 0.066 | 68 | 0.205 |
| 2 | 135 | 0.601 | 43 | 2.28 | 32 | 0.271 | 16 | 0.061 | 3.2 | 0.043 | 29 | 0.109 |
| 3 | 25 | 0.108 | 6.9 | 1.02 | 7 | 0.121 | 4.3 | 0.054 | 2.4 | 0.032 | 9.5 | 0.084 |
| 4 | 7.8 | 0.141 | 8.7 | 1.556 | 20 | 0.175 | 4.6 | 0.051 | 4.1 | 0.051 | 17 | 0.095 |
| 5 | 35 | 0.452 | 13 | 1.186 | 8.5 | 0.074 | 4.4 | 0.051 | AF | 0.02 | 6.4 | 0.04 |
| 6 | 18 | 0.294 | 13 | 1.121 | 8.3 | 0.123 | 2.9 | 0.048 | 0 | 0.032 | 5 | 0.039 |
| 8 | 17 | 0.137 | 7.6 | 0.676 | 5.4 | 0.16 | 14 | 0.085 | 0 | 0 | 6.4 | 0.037 |
| Session 2 | ||||||||||||
| Subject | S1 | S5 | S9 | S17 | S18 | S20 | ||||||
| −1 | 118 | 1.37 | 316 | 3.46 | 8.3 | 0.115 | 4.5 | 0.16 | 0 | 0.085 | 18 | 0.076 |
| 0.25 | 588 | 3.173 | 466 | 1.598 | 1099 | 0.373 | 1358 | 0.353 | 446 | 0.125 | 369 | 0.093 |
| 0.5 | 287 | 2.88 | 50 | 0.515 | 140 | 0.164 | 225 | 0.212 | 132 | 0.124 | 166 | 0.089 |
| 1 | 24 | 0.595 | 21 | 0.442 | 143 | 0.119 | 44 | 0.115 | 10 | 0.107 | 85 | 0.083 |
| 1.5 | 58 | 1.028 | 18 | 0.602 | 113 | 0.095 | 65 | 0.173 | 11 | 0.067 | 55 | 0.081 |
| 2 | 34 | 0.643 | 16 | 0.635 | 22 | 0.046 | 33 | 0.111 | 10 | 0.078 | 42 | 0.089 |
| 3 | 13 | 0.47 | 33 | 0.893 | 23 | 0.09 | 7.1 | 0.09 | 4.4 | 0.075 | 12 | 0.072 |
| 4 | 30 | 0.997 | 24 | 0.746 | 23 | 0.125 | 19 | 0.195 | 6.9 | 0.154 | 37 | 0.105 |
| 5 | 25 | 0.966 | 10 | 0.918 | 18 | 0.145 | 18 | 0.259 | 2.7 | 0.116 | 18 | 0.085 |
| 6 | 32 | 0.887 | 24 | 1.871 | 8.2 | 0.117 | 25 | 0.206 | 6.1 | 0.104 | 6.5 | 0.067 |
| 8 | 11 | 0.406 | 10 | 1.355 | 6.7 | 0.077 | 5.1 | 0.171 | 3 | 0.113 | 11 | 0.057 |
| Session 3 | ||||||||||||
| Subject | S1 | S5 | S9 | S17 | S18 | S10 | ||||||
| −1 | 69 | 1.234 | 506 | 1.067 | 9.2 | 0.079 | 338 | 0.137 | 17 | 0.098 | 5 | 0.086 |
| 0.25 | 168 | 3.042 | 752 | 1.109 | 1575 | 0.331 | 3207 | 0.135 | 585 | 0.199 | 248 | 0.081 |
| 0.5 | 43 | 1.154 | 544 | 1.086 | 461 | 0.197 | 333 | 0.059 | 293 | 0.194 | 57 | 0.066 |
| 1 | 70 | 0.836 | 51 | 0.372 | 139 | 0.09 | 169 | 0.075 | 65 | 0.095 | 62 | 0.064 |
| 1.5 | 42 | 0.907 | 133 | 0.776 | 185 | 0.128 | 106 | 0.074 | 36 | 0.077 | 33 | 0.066 |
| 2 | 37 | 0.502 | 93 | 0.65 | 70 | 0.092 | 128 | 0.091 | 13 | 0.105 | 19 | 0.056 |
| 3 | 7.6 | 0.358 | 34 | 0.658 | 22 | 0.11 | 24 | 0.041 | 14 | 0.096 | 12 | 0.043 |
| 4 | 19 | 0.618 | 62 | 1.515 | 51 | 0.136 | 101 | 0.135 | 19 | 0.142 | 7.7 | 0.062 |
| 5 | 23 | 0.76 | 47 | 1.424 | 31 | 0.16 | 86 | 0.126 | 21 | 0.087 | 7.9 | 0.071 |
| 6 | 30 | 1.41 | 32 | 1.351 | 23 | 0.108 | 64 | 0.123 | 18 | 0.153 | 6.7 | 0.068 |
| 8 | 3.5 | 0.383 | 11 | 1.135 | 29 | 0.228 | 22 | 0.063 | 17 | 0.106 | 4.2 | 0.062 |