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. 2015 Oct;12(10):1561–1571. doi: 10.1513/AnnalsATS.201503-172OT

Table 7.

GRADS study as a foundation for future studies of sarcoidosis

Associations of microbiomic and genomic signatures with clinical phenotypes provide for focused mechanistic studies on disease pathobiology
Genomic analyses from lung, epithelial brushings, and blood direct studies of local and systemic inflammatory pathways in lung and extrapulmonary disease
Validation of novel and previously discovered genomic biomarkers
Discovery of molecular phenotypes to inform personalized therapies based on relevant pathways
Molecular signatures of remitting vs. chronic sarcoidosis direct studies on manipulating relevant pathways and microflora for disease cure