Table 7.
Associations of microbiomic and genomic signatures with clinical phenotypes provide for focused mechanistic studies on disease pathobiology |
Genomic analyses from lung, epithelial brushings, and blood direct studies of local and systemic inflammatory pathways in lung and extrapulmonary disease |
Validation of novel and previously discovered genomic biomarkers |
Discovery of molecular phenotypes to inform personalized therapies based on relevant pathways |
Molecular signatures of remitting vs. chronic sarcoidosis direct studies on manipulating relevant pathways and microflora for disease cure |