Fig. 6.

Treatment with AMSC-derived exosomes alone has no effect on HCC growth in vivo. a, b Nude mice were inoculated subcutaneously with HepG2 cells. After 7 days of tumor growth, AMSC-derived exosomes were directly administered via intra-tumor injection. Tumor volume (a) and weight (b) measurement of HepG2 xenograft tumors at 35 days post-implantation (28 days after exosome administration). c Imaging of mice at 28 days after sole exosome treatment. Data are presented as means ± SE (n = 5). Exo naïve AMSC-derived exosomes, 122-Exo AMSC-122-derived exosomes, 67-Exo AMSC-67-derived exosomes