Fig. 2.
Target (CTLL-2/IL5Rα) to effector (NK92/NFAT-luciferase) cell ratio. CTLL-2/hIL5Rα cells and NK92/NFAT-luciferase cells grown at densities of 2.0 × 105 to 1.0 × 106 cells/mL were harvested, prepared at different ratios, and then mixed with benralizumab spiked in assay medium which ranged from 0.684 to 350 ng/mL. The mixture was incubated for 4.5 h, followed by adding Steady-Glo® as a substrate. The results are shown as relative luminescence units (RLU). Each data point was the mean result of duplicate wells. The different symbols represent the different target to effector ratios