Table 3.

CAPN10 SNP44 genotype distribution with or without consideration of identified copy number variations

Group (n)	Observed (expected) genotype frequency without consideration of CNVs			P HWE *	Group (n)	Observed (expected) genotype frequency with consideration of CNVs			P HWE **
	T/T	T/C	C/C			T/T	T/C	C/C
Case (n = 216)	182 (175.14)	25 (38.72)	9 (2.14)	1.91 × 10–7	Case (n = 126)	99 (98.67)	25 (25.66)	2 (1.67)	0.771
Controls (n = 192)	152 (144.39)	29 (44.23)	11 (3.39)	1.83 × 10–7	Controls (n = 120)	88 (87.55)	29 (29.90)	3 (2.55)	0.742

P-value reflects Hardy Weinberg Equilibrium (HWE) before^* and after^** consideration of identified copy number variations (CNVs).