Table 1. The Rosetta docking score to gp120 of the modified cyclotides versus KB1.

Groups	Number of compared structure	Binding score (Rosetta unit)
		Average	Maximum	Minimum
KB1 a	8 b	-4.07 (±0.76)	-3.08	-5.23
Modified KB1	910	-5.01 (±0.79)	-2.24	-7.95

^a global docking mode;

^b different orientations after clustering at the CD4-binding site