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| Groups | Average ΔSASA (Å2) | Average fraction of residues in the interaction interface (%) | |
|---|---|---|---|
| Loop 1–4 | Loop 5–6 | ||
| 8 orientations of KB1 | 1146.8 (±115.1) | 57.0 (±14.1) | 47.1 (±17.0) |
| 341 modified cyclotides | 1338.2 (±183.1) | 43.7 (±22.6) | 64.8 (±15.1) |
