Table 3. Lipinski´s rule of five of trans-Resveratrol Analogs and Amphotericin B.

Drug	CLogP	HBA	HBD	MW
PTEROSTILBENE	3.38	3	1	256.30
PICEATANNOL	2.48	4	4	244.24
POLYDATIN	0.84	8	6	390.38
OXYRESVERATROL	2.48	4	4	244.24
AMB	11.88	17	12	924.08

ClogP—octanol/water coefficiente partition; MW—molecular weight; MV—molecular volume;

HBD—number of hydrogen bonds donated; HBA—number of hydrogen bond accepted.