Table 1. Our “Mouse RPE signature genes” dataset: 64 mouse RPE genes with an average expression of at least 2.5 fold higher in the mouse RPE than in both the PR and the CH with an adjusted p-value smaller than 0.01.
| CH<RPE>PR genes | RPE compared to CH | RPE compared to PR | |||
|---|---|---|---|---|---|
| GeneName | SystematicName | adj.P.Val | FC RPE-CH | adj P value | FC RPE-PR |
| Rgr | ENSMUST00000022338 | 5,93E-03 | 4,9 | 5,90E-06 | 306,1 |
| LOC100045988 | XM_001475309 | 6,03E-03 | 4,6 | 3,81E-03 | 3,5 |
| Pon1 | NM_011134 | 1,01E-03 | 4,2 | 2,10E-07 | 95,8 |
| Rdh10 | NM_133832 | 1,46E-03 | 4,1 | 9,38E-08 | 75,1 |
| Arl6ip1 | NM_019419 | 4,41E-03 | 3,2 | 2,73E-06 | 24,6 |
| Rlbp1 | NM_020599 | 5,78E-03 | 3,2 | 4,29E-07 | 42,4 |
| Tbx5 | NM_011537 | 2,65E-03 | 3,2 | 3,61E-04 | 3,5 |
| Bmp4 | NM_007554 | 3,03E-03 | 3,2 | 2,31E-05 | 47,9 |
| F3 | NM_010171 | 1,42E-03 | 3,1 | 4,09E-07 | 102,2 |
| 5730469M10Rik | NM_027464 | 2,28E-03 | 3,1 | 1,03E-06 | 14,0 |
| Rrh | NM_009102 | 2,40E-03 | 3,1 | 8,94E-08 | 47,2 |
| Man1a | NM_008548 | 2,07E-04 | 3,0 | 6,11E-08 | 10,3 |
| Sema3c | NM_013657 | 5,52E-04 | 2,9 | 9,66E-08 | 504,3 |
| Vldlr | NM_013703 | 1,35E-03 | 2,9 | 1,79E-05 | 4,6 |
| Atp1b1 | NM_009721 | 2,54E-03 | 2,9 | 1,29E-07 | 34,1 |
| Ctsd | NM_009983 | 6,72E-03 | 2,9 | 6,81E-05 | 5,7 |
| Cspg5 | NM_001166273 | 5,34E-03 | 2,9 | 1,94E-06 | 15,1 |
| Cldn2 | NM_016675 | 6,79E-04 | 2,9 | 6,75E-07 | 7,8 |
| Sulf1 | NM_172294 | 4,05E-04 | 2,9 | 2,38E-07 | 22,9 |
| BC048943 | NM_001127685 | 1,48E-03 | 2,9 | 8,23E-05 | 3,4 |
| Slc39a12 | NM_001012305 | 6,97E-04 | 2,9 | 8,03E-08 | 123,3 |
| Loxl4 | NM_001164311 | 4,47E-04 | 2,8 | 7,52E-07 | 13,2 |
| NAP114398-1 | NAP114398-1 | 5,88E-04 | 2,8 | 2,70E-07 | 9,4 |
| Slc1a1 | NM_009199 | 6,31E-03 | 2,8 | 1,30E-07 | 27,2 |
| Slc6a13 | NM_144512 | 3,86E-03 | 2,8 | 9,05E-08 | 49,1 |
| Car12 | NM_178396 | 5,92E-03 | 2,8 | 2,86E-07 | 34,5 |
| Iqgap2 | NM_027711 | 3,55E-04 | 2,8 | 5,11E-08 | 13,4 |
| Hist2h2aa1 | NM_013549 | 2,53E-04 | 2,8 | 2,57E-07 | 5,7 |
| Tgfa | NM_031199 | 1,07E-03 | 2,8 | 2,66E-07 | 11,9 |
| Spon1 | NM_145584 | 3,68E-04 | 2,7 | 2,54E-07 | 7,4 |
| Flot2 | NM_008028 | 4,72E-03 | 2,7 | 1,50E-05 | 7,1 |
| Tmem27 | NM_020626 | 1,64E-03 | 2,7 | 3,15E-05 | 108,8 |
| Trhde | NM_146241 | 1,06E-03 | 2,7 | 7,15E-08 | 19,8 |
| Hist2h4 | NM_033596 | 8,85E-03 | 2,7 | 5,29E-05 | 7,0 |
| Itgb8 | NM_177290 | 2,57E-03 | 2,7 | 4,33E-07 | 14,9 |
| Cbfa2t3 | NM_001109873 | 6,18E-03 | 2,7 | 2,75E-06 | 11,8 |
| Tcfl5 | NM_178254 | 1,92E-03 | 2,7 | 4,74E-07 | 12,2 |
| Adora2b | NM_007413 | 3,61E-04 | 2,7 | 1,30E-07 | 37,0 |
| Spock1 | NM_009262 | 2,29E-03 | 2,7 | 1,28E-06 | 9,3 |
| Gpam | ENSMUST00000086868 | 8,06E-03 | 2,7 | 1,09E-03 | 3,0 |
| Acsl6 | NM_001033599 | 2,80E-03 | 2,7 | 2,96E-04 | 2,8 |
| Lrp2 | NM_001081088 | 6,73E-03 | 2,7 | 3,74E-06 | 10,7 |
| Slc6a20a | NM_139142 | 5,91E-04 | 2,6 | 3,38E-07 | 7,6 |
| Nt5dc2 | NM_027289 | 1,30E-03 | 2,6 | 9,65E-07 | 7,7 |
| Krt18 | NM_010664 | 2,04E-03 | 2,6 | 1,73E-06 | 7,2 |
| Slc16a8 | NM_020516 | 1,87E-03 | 2,6 | 2,46E-07 | 14,9 |
| Gabrb3 | NM_008071 | 3,18E-04 | 2,6 | 4,83E-06 | 3,3 |
| Mogat1 | NM_026713 | 2,79E-03 | 2,6 | 5,42E-07 | 12,9 |
| Hkdc1 | NM_145419 | 2,81E-03 | 2,6 | 7,31E-06 | 5,9 |
| Tmem56 | NM_178936 | 4,12E-03 | 2,6 | 1,71E-08 | 148,2 |
| Col4a4 | NM_007735 | 2,96E-03 | 2,6 | 3,44E-06 | 4,0 |
| Pebp4 | NM_028560 | 4,39E-04 | 2,6 | 4,15E-08 | 13,5 |
| Trpm3 | NM_001035246 | 1,61E-04 | 2,6 | 5,35E-09 | 23,2 |
| Hist1h4i | NM_175656 | 1,08E-03 | 2,6 | 4,09E-06 | 4,7 |
| A2m | NM_175628 | 1,55E-03 | 2,5 | 8,00E-05 | 3,0 |
| Bphl | NM_026512 | 8,30E-04 | 2,5 | 2,48E-06 | 3,1 |
| Slc7a10 | NM_017394 | 1,64E-03 | 2,5 | 3,27E-08 | 33,6 |
| Tshr | NM_011648 | 4,22E-04 | 2,5 | 1,22E-08 | 58,3 |
| Car14 | NM_011797 | 3,58E-03 | 2,5 | 2,60E-07 | 18,4 |
| Adra2c | NM_007418 | 4,16E-03 | 2,5 | 4,30E-08 | 54,8 |
| Fam13a | NM_153574 | 5,08E-04 | 2,5 | 2,20E-08 | 19,6 |
| Sgk3 | NM_133220 | 3,38E-03 | 2,5 | 3,87E-06 | 7,0 |
| Pde4b | NM_019840 | 5,03E-04 | 2,5 | 8,98E-07 | 5,0 |
| Slco1a4 | NM_030687 | 3,07E-04 | 2,5 | 6,65E-09 | 32,7 |