Table 4. Characteristics of different genotypes within athletes and non-athletes (irrespective of their gender).
| Athletes (VO2 max >50ml/kg/min) | Non-athletes (VO2 max >50ml/kg/min) | ||||
|---|---|---|---|---|---|
| Glu/Glu | Glu/Asp + Asp/Asp | Glu/Glu | Glu/Asp+ Asp/Asp | p | |
| n | 64 | 62 | 84 | 71 | - |
| LVEF (%) | 58.3±8.1 | 58.7±4.5 | 59.1±2.4 | 60.0±6.7 | 0.688 |
| LVEDVi (ml/m 2 ) | 115.1±20.5 * | 117.0±14.9 * | 92.1±14.6 | 94.4±9.3 | <0.001 |
| LVESVi (ml/m 2 ) | 49.2±13.3 * | 48.5±9.3 * | 37.8±7.8 | 37.9±7.6 | <0.001 |
| LVMi (g/m 2) | 77.9±23.1 * | 83.5±16.2 * | 60.3±15.3 | 63.2±11.2 | <0.001 |
| LVSVi (ml/m 2 ) | 66.4±7.6 * | 68.5±8.7 * | 54.1±7.6 | 56.1±8.2 | <0.001 |
| RVEF (%) | 57.7±8.1 | 58.1±4.4 | 58.3±4.1 | 58.4±5.8 | 0.427 |
| RVEDVi (ml/m 2 ) | 117.8±19.9 * | 124.4±19.1 * | 95.6±17.6 | 95.4±9.8 | <0.001 |
| RVESVi (ml/m 2 ) | 53.0±10.5 * | 53.4±12.1 * | 40.4±11.0 | 38.7±6.5 | <0.001 |
| RVSVi (ml/m 2 ) | 64.3±9.8 # * | 71.1±9.6 * | 56.6±6.7 | 56.8±7.8 | <0.001 |
| RVMi (g/m 2 ) | 27.4±6.0 # * | 31.7±5.5 * | 25.3±4.7 | 23.3±3.4 | <0.001 |
n—number of individuals; LVEF—left ventricular ejection fraction; LVEDVi—left ventricular end-diastolic volume index; LVESVi—left ventricular end-systolic ventricular index; LVMi—left ventricular mass index; LVSVi—left ventricular stroke volume index; RVEF—right ventricular ejection fraction; RVEDVi—right ventricular end-diastolic volume index; RVESVi—right ventricular end-systolic volume index; RVSVi—right ventricular stroke volume index; RVMi—right ventricular mass index
Analysis of variance showed significant differences among the inspected groups: athletes and non-athletes with and without the Aspartate allele. Post hoc tests revealed a significant influence of the genotype on resting RVSVi and RVMi in athletes,
# p<0.001 vs Asp carriers within the athlete group.
Athletic status had significant influence on all parameters with the exception of LVEF and RVEF,
* p<0.001 vs non-athletes irrespective of genotype.