Table 3. Brachial (BA) and superficial femoral artery (SFA) endothelium-dependent vasodilation through flow-mediated dilation (FMD), peak diameter and endothelium-independent dilation (GTN), and common carotid artery (CCA) intima-media thickness (IMT).
| CT (n = 10) | HIT (n = 10) | P-value | |||||
|---|---|---|---|---|---|---|---|
| Pre | Post | Pre | Post | Time | Group | Time*Group | |
| BA diameter (mm) | 4.5±0.5 | 4.5±0.5 | 4.4±0.9 | 4.4±0.8 | 0.83 | 0.68 | 0.86 |
| BA FMD (%) | 5.2±2.5 | 4.8±3.0 | 5.3±2.6 | 4.7±2.5 | 0.33 | 0.92 | 0.98 |
| BA FMD (%, scaled) | 5.3±2.5 | 4.8±2.5 | 5.2±2.5 | 4.6±2.5 | 0.47 | >0.999 | 0.91 # |
| BA SRAUC (s, 103) | 19.9±9.6 | 18.6±7.4 | 17.8±9.2 | 22.3±7.7 | 0.42 | 0.80 | 0.14 |
| BA GTN (%) | 17.6±7.0 | 16.3±6.5 | 16.8±8.7 | 15.2±4.9 | 0.33 | 0.74 | 0.92 |
| BA GTN (%, scaled) | 17.9±4.5 | 16.6±4.5 | 16.1±4.5 | 14.6±4.5 | 0.42 | 0.27 | 0.94 |
| BA FMD-GTN ratio | 0.34±0.21 | 0.33±0.24 | 0.42±0.30 | 0.34±0.15 | 0.46 | 0.63 | 0.82 |
| BA CADC (%) | 10.6±6.4 | 11.3±4.8 | 16.1±7.4 | 13.4±5.5 | 0.52 | 0.12 | 0.26 |
| BA CADC (%, scaled) | 11.0±4.2 | 12.0±4.2 | 15.0±4.2 | 12.8±4.2 | 0.72 | 0.11 | 0.27 |
| BA peak blood flow (mL/min) | 794±139 | 862±261 | 711±264 | 556±165 | 0.38 | 0.56 | 0.46 |
| SFA diameter (mm) | 7.1±1.2 | 6.9±1.2 | 6.7±1.1 | 6.5±1.0 | 0.38 | 0.48 | 0.88 |
| SFA FMD (%) | 3.3±1.9 | 5.1±4.8 | 4.2±1.8 | 3.4±2.8 | 0.58 | 0.74 | 0.19 |
| SFA FMD (%, scaled) | 3.5±2.9 | 5.1±2.9 | 4.1±2.9 | 3.1±2.9 | 0.74 | 0.50 | 0.19 |
| SFA SRAUC (s, 103) | 9.2±5.6 | 10.4±10.8 | 13.5±7.2 | 6.9±3.9 | 0.11 | 0.80 | 0.07 |
| CA IMT (mm) | 0.80±0.13 | 0.76±0.20 | 0.72±0.12 | 0.67±0.16 | 0.20 | 0.24 | 0.96 |
| CA IMT-to-lumen ratio | 0.12±0.02 | 0.11±0.02 | 0.11±0.02 | 0.11±0.02 | 0.40 | 0.59 | 0.45 |
Data is presented as mean±SD. P-values refer to 2-way repeated measures ANOVA between the 2 training groups.
# For statistical reasons, data was analyzed with three separate tests to determine time, group and time*group P-values. Due to technical problems, BA GTN/FMD-GTN ratio/peak blood flow was available for 9 subjects in the HIT-group and SFA FMD was available for 8 subjects in the HIT-group. CCA IMT and IMT-to-lumen ratio were available for 8 subjects in each group. SRAUC; shear rate area-under-the-curve. CADC; conduit artery dilating capacity.