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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Ann N Y Acad Sci. 2015 Apr 30;1362(1):98–109. doi: 10.1111/nyas.12760

Figure 3. B-1–like cells are present in higher primates.

Figure 3

A) Sample gating strategy to identify B cells in NHP tissues. B cells were defined as either CD19+CD20+ cells present within the lymphocyte gate. CD11b expression (solid line) by B cells in AGM peritoneal cavity (P. cavity), omentum, spleen, and blood is shown in histograms in the lower panel. B) FSC, IgM, CD21, and CD19 expression by CD11b+ (solid line) and CD11b− B cells (gray shading), gated as shown in (A). C) Constitutive active Stat3(p705) expression (solid line) by CD19+ spleen B and peritoneal CD11b− and CD11b+ B cells in AGMs (top histograms) and mice (bottom histograms). Histograms with dashed lines indicate intracellular mAb isotype control staining. Adapted from Yammani and Haas52.