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Effect of a total daily dose of compactin sodium on the final pravastatin concentration and bioconversion rate of Streptomyces xanthochromogenes S 33-1
| Daily compactin dose (g/L) | Pravastatin concentrationa (g/L) | Bioconversion ratea (%) |
|---|---|---|
| 1 | 0.91 ± 0.04 | 91.0 ± 4.0 |
| 1.5 | 1.31 ± 0.03 | 87.3 ± 2.0 |
| 2 | 1.65 ± 0.05 | 83.0 ± 2.5 |
| 2.5 | 0.1 ± 0.05 | 4.0 ± 2.0 |
aData obtained for the improved fermentation medium
