Table 1.

Causative genes of hydrocephalus

HPE	Location of chromosome	Casusal genes	Authors	References23,24)
HPE2	2p21	SIX3	Wallis DE	Nature Genet 22: 196–198, 1999
HPE3	7p36	Sonic hedgehog (SHH)	Roessler E	Nature Genet 14: 357–360, 1996
HPE4	18p11.3	TGIF1	Gripp KW	Nature Genet 25: 205–208, 2000
HPE5	13q32	ZIC2	Brown SA	Nature Genet 20: 180–183, 1998
HPE7	9q22.3	PATCHED-1(PTCH1)	Ming JE	Am J Hum Genet 71: 1017–1032, 2002
HPE9	2q14	GLI2	Roessler E	Proc Natl Acad Sci USA 100: 13424–13429, 2003
HPE10	1q42	DISP1	Roessler E	Hum Genet 125: 393–340, 2009
HPE11	11q24.2	CDON	Bae GU	Am J Hum Genet 89: 231–240, 2011
HPE12	6q27	DLL1	Dupe V	Hum Mol Genet 20: 1122–1131, 2011
	3p21–p23	TDGF1	De la Cruz JM	Hum Genet 110: 422–428, 2002
	6q22.31–q23.2	EYA4	Abe Y	Hum Mutat 30: E946–E955, 2009
	8q24.3	FAST1(FOXH1)	Cohen MM Jr	Am J Med Genet 123A: 5–28, 2003
	9q21.33	GAS1	Ribeiro LA	Am J Med Genet 152A: 1688–1694, 2010
	10q22.4	NODAL	Roessler E	Mol Genet Metab 98: 225–234, 2009
	10q24	FGF8	Arauz RF	Mol Syndromol 1: 59–66, 2010
	11q13.4	DHCR7
HPE1	21q22
HPE6	2p37.1
HPE8	14q13

HPE: hydrocephalus.