Kinetic Curve Assessment |
Maximum enhancement |
Maximum contrast enhancement |
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Time to peak (s) |
Time at which the maximum enhancement occurs |
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Uptake rate (1/s) |
Uptake speed of the contrast enhancement |
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Washout rate (1/s) |
Washout speed of the contrast enhancement |
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Curve shape index |
Difference between late and early enhancement |
Enhancement-Variance Kinetics |
Maximum variance of enhancement |
Maximum spatial variance of contrast enhancement over time |
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Time to peak at maximum variance (s) |
Time at which the maximum variance occurs |
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Enhancement variance increasing rate (1/s) |
Rate of increase of the enhancement-variance during uptake |
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Enhancement variance decreasing rate (1/s) |
Rate of decrease of the enhancement-variance during washout |
Enhancement Texture |
Angular second moment (Energy) |
Image homogeneity |
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Contrast |
Local image variations |
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Correlation |
Image linearity |
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Entropy |
Randomness of the gray-levels |
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Sum of squares (Variance) |
Spread in the gray-level distribution |
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Difference entropy |
Randomness of the difference of neighboring voxels' gray-levels |
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Difference variance |
Variations of difference of gray-levels between voxel-pairs |
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Inverse difference moment |
Image homogeneity |
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Sum average |
Overall brightness |
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Sum entropy |
Randomness of the sum of gray-levels of neighboring voxels |
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Sum variance |
Spread in the sum of the gray-levels of voxel-pairs distribution |
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Information measure of correlation (IMC) 1 |
Nonlinear gray-level dependence |
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Information measure of correlation (IMC) 2 |
Nonlinear gray-level dependence |
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Maximum correlation coefficient |
Nonlinear gray-level dependence |
Morphology |
Sphericity/circularity |
Similarity of the lesion shape to a sphere |
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Irregularity |
Deviation of the lesion surface from the surface of a sphere |
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Margin sharpness |
Mean of the image gradient at the lesion margin |
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Variance of margin sharpness |
Variance of the image gradient at the lesion margin |
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Variance of radial gradient histogram |
Degree to which the enhancement structure extends in a radial pattern originating from the center of the lesion |