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. 2015 Oct 31;12:196. doi: 10.1186/s12974-015-0418-1

Fig. 4.

Fig. 4

Volcano plots demonstrating different miRNA expression levels in whole blood in two-group comparisons. Volcano plots showing the log2 fold differences of the average miRNA expression in whole blood on the x-axis and the negative decade logarithm of the unadjusted p value on the y-axis. a Patients with NMOSD vs. patients with CIS/RRMS, b patients with NMOSD vs. healthy controls, c patients with CIS/RRMS vs. healthy controls. The horizontal lines indicate a p value of 10−3. CIS clinically isolated syndrome, RRMS relapsing-remitting multiple sclerosis, NMOSD neuromyelitis optica spectrum disorder