Table 5.
Incidence rate ratios (IRR) for associated outcomes within a year following herpes zoster diagnosis
| CVD (excl. stroke) | Stroke | Sepsis | Bell’s palsy | |||||
|---|---|---|---|---|---|---|---|---|
| n | IRRa (95 % CI) | n | IRRa (95 % CI) | n | IRRa (95 % CI) | n | IRRa (95 % CI) | |
| All cases | 64 | 1.82 (1.42–2.33) | 111 | 1.34 (1.12–1.62) | 37 | 1.47 (1.06–2.03) | 71 | 10.6 (8.33–13.4) |
| Sex | ||||||||
| Men | 26 | 1.62 (1.10–2.38) | 49 | 1.30 (0.98–1.72) | 15 | 1.23 (0.74–2.05) | 43 | 15.7 (11.6–21.3) |
| Women | 38 | 1.99 (1.45–2.74) | 62 | 1.38 (1.08–1.77) | 22 | 1.68 (1.11–2.56) | 28 | 6.99 (4.80–10.2) |
| p-value b | 0.41 | 0.75 | 0.36 | <0.01 | ||||
| Age (years) | ||||||||
| 0–39 | 0 | . | 4 | 10.3 (3.87–27.6) | 3 | 9.10 (2.93–28.3) | 15 | 23.4 (14.0–38.9) |
| 40–49 | 1 | 1.15 (0.16–8.16) | 0 | . | 3 | 9.42 (3.02–29.3) | 1 | 2.62 (0.37–18.6) |
| 50–59 | 12 | 3.51 (1.99–6.19) | 2 | 0.44 (0.11–1.76) | 0 | . | 6 | 7.23 (3.23–16.2) |
| 60–69 | 21 | 2.68 (1.75–4.12) | 13 | 1.12 (0.65–1.92) | 3 | 0.79 (0.25–2.44) | 17 | 9.09 (5.61–14.7) |
| 70–79 | 16 | 1.37 (0.84–2.25) | 35 | 1.47 (1.05–2.04) | 6 | 0.79 (0.35–1.76) | 13 | 7.69 (4.42–13.4) |
| 80+ | 14 | 1.29 (0.76–2.18) | 57 | 1.38 (1.07–1.80) | 22 | 1.82 (1.19–2.77) | 19 | 14.4 (9.03–23.0) |
| p-value c | 0.06 | <0.01 | <0.01 | 0.01 | ||||
aAdjusted for age and sex
bFrom Wald test of interaction between HZ and sex
cFrom Wald test of interaction between HZ and age group