Table 1.

Apparatus and laboratory findings during the observation period after ibogaine intoxication

Type of analysis	Day 1	Day 2	Day 3	Day 4	Day 5	Month 3
Computed tomography	–	No pathological findings	–	–	–
Magnetic resonance imaging	–	–	No pathological findings	–	–
Electrocardiogram	Sinus tachycardia (>120 beats per minute)/Sinus rhythm	Sinus rhythm	Sinus rhythm 55 beats per minute; QTc: 100 %	–	–
Electroencephalogram		–	–	Irregular alpha rhythm, significant portion of diffuse theta waves, no focal slowing, no epileptiform discharges	–	Regular alpha rhythm, no focal slowing, no epileptiform discharges
Laboratory findings						Reference values
White blood cell count (×103/μl)	11.7	10.6	6.2	5.1	4.4	4.0–9.4
Platelet count (×103/μl)	248	164	136	127	176	150–440
Lymphocyte count (%)	5.8	11.7	25	29.4	28.0	25–40
Neutrophil count (%)	87.8	79.2	62.4	59.9	58.8	50–75
Creatinine (mg/dl)	1.24	0.84	0.75	0.79	0.76	<1.2
Creatine-kinase (U/l)	–	–	370	234	194	<190
C-reactive protein (mg/l)	0.69	–	0.71	0.39	0.35	0.0–0.5
Carbohydrate-deficient transferrin (%)	–	–	–	–	1.59	<2.6
Ibogaine concentration in hair sample (pg/mg)			22			–
Noribogaine concentration in hair sample (pg/mg)			70			–
Noribogaine concentration in urine sample (ng/mg)			9.2			–

Pathological findings are marked in bold. All other routine parameters (for example liver enzymes, electrolytes, coagulation status, triglycerides, cholesterol, thyroid-stimulating hormone, free triiodothyronine, and free thyroxine), as well as the screening for drugs in the patient’s urine (benzodiazepine, amphetamine, morphine/opiate/heroin, barbiturates, ecstasy/3,4-methylenedioxy-methamphetamine, methadone, cocaine metabolites, methamphetamine, tetrahydrocannabinol, fentanyl, tricyclic antidepressants, buprenorphine), and in the serum (barbiturates, benzodiazepine, tricyclic antidepressants) showed no pathological findings