Table 2.
Patient characteristics
| No anticoagulation | Heparin | Citrate | ||
|---|---|---|---|---|
| n = 13 | n = 8 | n = 21 | P | |
| Age, yrs | 70 (34–84) | 57 (23–81) | 64 (32–84) | 0.49 |
| Sex, male | 7 (54) | 6 (75) | 14 (75) | 0.59 |
| Weight, kg | 70 (50–100) | 74 (55–135) | 78 (60–110) | 0.41 |
| Sepsis | 5 (39) | 5 (63) | 8 (38) | 0.46 |
| APACHE II at ICU admission | 28 (11–42) | 22 (15–37) | 25 (14–41) | 0.47 |
| SAPS II at ICU admission | 75 (43–112) | 47 (37–77) | 52 (32–86) | 0.002 |
| Creatinine, μmol/L | 249 (100–410) | 420 (156–626) | 326 (47–622) | 0.01 |
| Urea, mmol/L | 21 (6–48) | 32 (12–97) | 21 (6–41) | 0.25 |
| Leukocytes, ×109/L | 8 (1–17) | 12 (7–20) | 12 (1–26) | 0.29 |
| Platelets, ×109/L | 65 (22–173) | 167 (44–352) | 118 (35–332) | 0.03 |
| Prescribed CVVH dose, mL/kg/h | 22 (16–32) | 22 (11–32) | 23 (16–31) | 0.68 |
Median (and range) or number (percentage). APACHE II Acute Physiology and Chronic Health Evaluation II, ICU intensive care unit, SAPS II Simplified Acute Physiology Score II