Table 1.
Clinical characteristics (means ± SD) of the study population at the age of 50 years
| Cases (n = 325) | Controls (n = 444) | P | |
|---|---|---|---|
| Age (years) | 50 ± 0 | 50 ± 0 | |
| Gender (male) % | 59 | 63 | 0.279 |
| Blood pressure medication (%) | 73 | 0 | <0.000 |
| Smoking (%) | 27 | 25 | 0.588 |
| Body mass index (kg/m2) | 28.8 ± 5.1 | 25.5 ± 3.6 | <0.000 |
| Cholesterol (mmol/l) | 5.40 ± 0.98 | 5.37 ± 0.88 | 0.789 |
| Glucose (mmol/l) | 5.17 ± 1.30 | 4.86 ± 0.54 | <0.000 |
| Systolic blood pressure (mm Hg) | 142.7 ± 16.7 | 129.3 ± 14.8 | <0.000 |
| Diastolic blood pressure (mm Hg) | 92.8 ± 8.9 | 84.4 ± 9.1 | <0.000 |
| NLRP3 gene polymorphism rs7512998 (CC/TC/TT) % | 1.5/28.9/69.6 | 2.5/27.8/69.7 | 0.647 |
| rs7512998 (CC+TC/TT) % | 30.4/69.6 | 30.3/69.7 | 0.626 |