Table 1.

Simulation examples: estimated means and standard deviations (in parentheses) of the empirical Youden index J over 100 replications

	n=100	n=250	n=500
Example 1
LKME	0.604 (0.0042)	0.628 (0.0019)	0.641 (0.0018)
GKME	0.572 (0.0063)	0.604 (0.0029)	0.623 (0.0023)
MMM	0.455 (0.0032)	0.470 (0.0021)	0.483 (0.0020)
MVN	0.633 (0.0018)	0.638 (0.0014)	0.647 (0.0012)
KSM	0.388 (0.0180)	0.458 (0.0104)	0.490 (0.0106)
SWM	0.555 (0.0065)	0.594 (0.0044)	0.611 (0.0035)
LR	0.628 (0.0022)	0.639 (0.0017)	0.646 (0.0017)
TREE	0.490 (0.0068)	0.525 (0.0047)	0.559 (0.0029)
Example 2
LKME	0.636 (0.0075)	0.690 (0.0025)	0.710 (0.0015)
GKME	0.612 (0.0054)	0.654 (0.0045)	0.696 (0.0016)
MMM	0.609 (0.0033)	0.622 (0.0025)	0.622 (0.0022)
MVN	0.573 (0.0065)	0.571 (0.0047)	0.563 (0.0040)
KSM	0.214 (0.0281)	0.046 (0.0164)	0.047 (0.0171)
SWM	0.447 (0.0094)	0.426 (0.0078)	0.429 (0.0065)
LR	0.648 (0.0054)	0.675 (0.0028)	0.678 (0.0025)
TREE	0.433 (0.0052)	0.512 (0.0039)	0.555 (0.0036)
Example 3
LKME	0.296 (0.0091)	0.367 (0.0053)	0.389 (0.0049)
GKME	0.511 (0.0052)	0.568 (0.0028)	0.592 (0.0022)
MMM	0.423 (0.0035)	0.434 (0.0021)	0.443 (0.0018)
MVN	0.344 (0.0050)	0.371 (0.0045)	0.377 (0.0041)
KSM	0.192 (0.0085)	0.193 (0.0084)	0.202 (0.0086)
SWM	0.370 (0.0057)	0.406 (0.0028)	0.417 (0.0025)
LR	0.307 (0.0043)	0.316 (0.0030)	0.320 (0.0026)
TREE	0.424 (0.0059)	0.477 (0.0042)	0.528 (0.0031)
Example 4
LKME	0.103 (0.0102)	0.150 (0.0098)	0.209 (0.0089)
GKME	0.529 (0.0078)	0.626 (0.0050)	0.682 (0.0028)
MMM	0.184 (0.0084)	0.227 (0.0034)	0.236 (0.0026)
MVN	0.109 (0.0071)	0.152 (0.0056)	0.189 (0.0054)
KSM	0.188 (0.0050)	0.213 (0.0035)	0.220 (0.0028)
SWM	0.255 (0.0078)	0.293 (0.0050)	0.307 (0.0039)
LR	0.002 (0.0023)	0.004 (0.0008)	0.011 (0.0007)
TREE	0.257 (0.0143)	0.364 (0.0111)	0.368 (0.0101)