Table 3.

Univariate logistic regression model of demographic and imaging determinants of cognitive dysfunction among subjects

	Normal vs vCIND			vCIND vs PSD			Normal vs (vCIND + PSD)
	OR	95 % CI	p value*	OR	95 % CI	p value*	OR	95 % CI	p value*
Age >60 years	3.21	0.98–10.45	0.053	2.54	0.42–15.21	0.308	3.97	1.30–12.13	0.016
Female gender	2.24	0.72–6.95	0.163	1.19	0.23–6.17	0.835	2.34	0.81–6.74	0.116
Education <7 years	6.67	1.92–23.18	0.003	3.50	0.37–33.56	0.277	8.52	2.58–23.12	<0.001
Total WMH score	1.06	0.97–1.13	0.123	1.02	0.95–1.09	0.580	1.06	1.00–1.13	0.073
Periventricular WMH score	1.20	0.92–1.57	0.181	1.10	0.76–1.60	0.610	1.22	0.96–1.56	0.102
Deep WMH score	1.06	0.98–1.15	0.145	1.02	0.95–1.10	0.600	1.07	0.99–1.15	0.094
Log_ICV	0.22	0.001–5462.00	0.809	0.02	0.001–10,385.0	0.247	0.01	0.001–1144.1	0.439
Log_TBV	0.04	0.01–137.28	0.230	0.03	0.01–0.023	0.024	0.04	0.01–0.20	0.025
Log_VenVol	13.44	0.52–347.02	0.117	1.22	0.020–74.90	0.924	18.6	0.81–429.36	0.067
MTLA rating	1.91	1.19–3.06	0.007	1.10	0.59–2.07	0.759	2.05	1.28–3.27	0.003

vCIND vascular cognitive impairment no dementia, PSD post-stroke dementia, CSID Community Screening Instrument for Dementia, MMSE Minimental State Examination, V-NB vascular neuropsychological battery, ICV intracranial volume, TBV total brain volume, VenVol ventricular volume, MTA medial temporal lobe atrophy rating, WMH white matter hyperintensity, OR odds ratio, CI confidence interval

* p value = significant p values are in italics