Table 1.

Diagnostic performance of imaging modalities (n = 92). Results including confidence intervals are listed

Performance	Mammography	Breast ultrasound	MRI	Breast-specific gamma imaging
Sensitivity/TPRa	0.85 ± 0.07 (57/67)	0.99 ± 0.02 (66/67)	0.88 ± 0.07 (59/67)	0.90 ± 0.06 (60/67)
Specificity/TNRa	0.28 ± 0.09 (7/25)	0.20 ± 0.08 (5/25)	0.40 ± 0.10 (10/25)	0.56 ± 0.10 (14/25)
Precision/PPVa	0.76 ± 0.09 (57/75)	0.77 ± 0.09 (66/86)	0.80 ± 0.08 (59/74)	0.85 ± 0.07 (60/71)
NPVa	0.41 ± 0.10 (7/17)	0.83 ± 0.08 (5/6)	0.56 ± 0.10 (10/18)	0.67 ± 0.10 (14/21)
Accuracya	0.70 ± 0.09 (64/92)	0.77 ± 0.09 (71/92)	0.75 ± 0.09 (69/92)	0.80 ± 0.08 (74/92)
AUC (p-value)	0.64 (0.095)	0.59 (0.041)	0.57 (0.047)	0.73
Kappa	0.15	0.24	0.31	0.48
McNemar	0.19	0.00	0.21	0.48

AUC, area under curve or balanced accuracy with p-values from DeLong's test for receiver operating characteristic curves compared with breast-specific gamma imaging; McNemar, p-value for comparison of imaging modalities and histologically confirmed results; NPV, negative predictive value (describes the ability of a negative test to rule out malignancy); PPV, positive-predictive value (describes the ability of a positive test to predict malignancy); TNR, true negative rate; TPR, true positive rate.

^aNumbers for calculation in parenthesis.