Table 3.

Analysis of combination drug effects of TCEE with cisplatin or doxorubicin in Hep3B and HepJ5 cells. Combination drug index (CDI) was analyzed on cell viability data obtained from Figure 3 by using the CalcuSyn software. CDI < 1 indicated a synergistic effect, CDI = 1 indicated an additive effect, and CDI > 1 indicated an antagonistic effect.

		Combination drug index
		Hep3B	HepJ5
		Plus 0.2 mg/mL TCEE	Plus 0.5 mg/mL TCEE
Cisplatin (μM)	1	0.52	0.75
	2	0.59	0.77
	4	0.64	0.96
	6	0.61	1.08
	8	0.48	1.03
	10	0.47	0.88
	20	1.16	0.55
Doxorubicin (μM)	0.5	0.61	1.39
	1	0.77	1.04
	1.5	0.74	0.71
	2	0.38	0.79
	3	0.32	0.72
	4	0.58	0.58
	5	0.67	0.78