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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Pharm Res. 2015 Jun 26;32(12):3827–3836. doi: 10.1007/s11095-015-1743-x

Table II. Evaluation of anti-Pfs25 antibody titers in mice immunized with CHrPfs25.

(a) CHrPfs25 adsorbed to alum and vaccinated via IP and IM routes
Antibody titers
Groups Prime (Day 21) 1st Boost (Day 31) 2nd Boost (Day 52)
IP 0 320,000 640,000
IM 800 320,000 640,000
(b) CHrPfs25 admixed with NE and PGA-NPs administered via IM route
Antibody titers
Groups Prime (Day 21) 1st Boost (Day 31) 2nd Boost (Day 52)
8% NE 400 160,000 320,000
4% NE 800 320,000 640,000
4% NE+MPL-A 400 80,000 640,000
4% NE+Chitosan 0 20,000 640,000
PLGA-NP (20 mg/mL) 800 80,000 320,000
PLGA-NP (10 mg/mL) 800 20,000 160,000
HHS Vulnerability Disclosure