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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Exp Eye Res. 2015 Jun 9;141:57–73. doi: 10.1016/j.exer.2015.06.005

Figure 3. OCT Phenotyping in the NHP EG Model - Part 3: Automated and manually-corrected segmentation for the ONH rim (left and middle), RNFL (upper right) and Macula (lower right).

Figure 3

A large literature now supports the concept of a minimum rim measurement made from BMO in humans and NHPs (Chen, 2009; He et al., 2014a; He et al., 2014b; Patel et al., 2014a; Patel et al., 2014b; Povazay et al., 2007; Strouthidis et al., 2011b; Yang et al., 2014b). The logic for this approach has also been articulated (Chauhan and Burgoyne, 2013; Chauhan et al., 2013; Reis et al., 2012a). Several OCT manufacturers are now automatically segmented BMO-MRW (left, and by clinical clock-hour - left middle), peripapillary RNFL (upper right) and macula (lower right) anatomy which can then be manually corrected and exported for analysis.