Table 2.
Total energy expenditure and its components measured in the room calorimeter at baseline and after 5 mo of treatment in participants randomized to gonadotropin releasing hormone agonist therapy plus add-back of placebo or estradiol
| GnRHAG+PL |
GnRHAG+E2 |
|||
|---|---|---|---|---|
| Baseline | 5 mo | Baseline | 5 mo | |
| Resting EE, kcal/d | 1,455.4 (181.4) | 1,401.1 (167.9)*,† | 1,456.1 (167.9) | 1,462.6 (169.8) |
| Total EE, kcal/d | 2,226.0 (321.7) | 2,098.0 (307.7)* | 2,255.7 (270.7) | 2,159.5 (299.6)* |
| Sleep EE, kcal/min | 1.02 (0.15) | 0.95 (0.16)* | 1.05 (0.12) | 0.97 (0.10)* |
| Exercise EE, kcal/min | 5.47 (1.21) | 5.01 (1.24)* | 5.48 (1.18) | 5.18 (1.41) |
| Thermic effect of feeding, kcal/min | 0.41 (0.11) | 0.45 (0.12) | 0.41 (0.11) | 0.46 (0.14) |
| Nonexercise EE, kcal | 197.2 (110.3) | 216.9 (83.2) | 182.7 (53.7) | 223.9 (108.1) |
Values are means ± SD; GnRHAG+PL, n = 24; GnRHAG+E2, n = 21. EE, energy expenditure.
*
Within-group change, P < 0.05;
†
between-group difference in change, P < 0.05.