Table 1.

Nutraceuticals effectively control the progression of colon cancer cell.

Nutraceuticals	Molecular mechanism	Cancer cell line	Ref.
α-Tocopheral	Antiproliferation, oxidative phosphorylation	HCT-116	49
Silbinin	Reduced cell growth	HT-29	49
Fenugreek	Cytokines, redox reactions	HT-29	50
Curcumin (turmeric)	Stimulation of MAPk, Plsk/Akt	HT29	51
Iron foods	Transferrin receptor (TfR1)	Cao-2, HCT-116	52
Graph seed	Control the signaling related epigenetics, oncogene expression	HCT-116	53
Zerumbone	Upregulation of DR4 and DR5 MMP-9, Cdc family	HCT-116	54
Allicin	Inhibit the over expression TNF-α family gene	HCT-116	55
Rhizochalin	Caspase-3 and PRAP activation	HT-29	56
Fucoxanthin	Induce apoptosis	Caco-2, HT-29	57
Protein and peptides (milk)	Hypoproliferation of epitheliam	HCT-116	58
Garcinol	Inhibition of tyrosine phosphorylation	HT-29	59
Xanthohumol	Upregulation of caspase-3, -8, -9	HT-29	60
Boswellic acid	Decrease in cyclin D1 expression	HT-29	61
β-Escin	Induced cell cycle arrest at the G1/S phase	HT-29	62
Quercetin	Inhibition of cyclin D1 expression	SW 480	63
Fisetin	Activation of NF-κB and decrease in cyclin D1 expression	HT-29	34