Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jul 15;4(4):307–312. doi: 10.1016/j.apsb.2014.06.002

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).

PMC Copyright notice

Scheme 1 — Synthetic routes for N-substituted sophocarpinic acid analogs. Reagents and conditions: (a) 10% KOH/H₂O, reflux, 7 h; then 3 mol/L HCl, pH 5–6; (b) diphenyldiazomethane, MeOH/petroleum ether(boiling range 30–60 °C), overnight; (c) (1) substituted benzyl chloride/bromine or benzenesulfonyl chloride, CH₂Cl₂ or MeCN, K₂CO₃, r.t., overnight; (2) flash column chromatography; (d) m-cresol, 80 °C, 8–9 h.