Skip to main content
. 2015 Oct 29;6:553. doi: 10.3389/fimmu.2015.00553

Figure 1.

Figure 1

Boost in IFNγ, IL-2, and TNFα following ZOSTAVAX vaccination. Whole blood was drawn from 21 subjects prior to and following ZOSTAVAX (3–4 weeks) vaccination. Within 2 h of blood draw, the specimen was stimulated with VZV peptide pools, VZV lysate (positive control), MRC5, and DMSO (negative controls) for 24 h. Plasma was then harvested and tested for the presence of (A) effector cytokines – IFNγ, IL-2, and TNFα; (B) pro-inflammatory cytokines – IL-1β and IL-10; and (C) anti-inflammatory cytokine IL-10, by using the Meso Scale Discovery kits. Each dot represents one subject. The geometric mean ± 95% confidence interval is shown for all data sets. Horizontal broken line denotes the lowest limit of detection for all cytokines.