Table 2.
Summary of syndromic profiles of emotional sound processing in patients relative to healthy controls
Disease group | Pupil responses |
Valence rating | Semantic performance† | |
---|---|---|---|---|
Overall reactivity | Valence coupling∗ | |||
bvFTD | Impaired‡ | Impaired | Preserved | Impaired |
SD | Impaired§ | Preserved|| | Preserved | Impaired¶ |
PNFA | Impaired‡ | Preserved | Preserved | Preserved |
AD | Preserved | Impaired | Impaired§ | Preserved |
Abbreviations: bvFTD, behavioral variant frontotemporal dementia; SD, semantic dementia; PNFA, progressive nonfluent aphasia; AD, Alzheimer's disease. See text for details.
Correlation of pupil response with affective sound valence ratings by that group.
Nonverbal auditory semantic classification task.
Also relative to AD group.
Relative to all other groups.
Impaired if referenced to healthy control (rather than patients' own) affective ratings.
Also relative to PNFA group.