Table 5. Identified metabolite associated with CON in the CON–CWP OPLS-DA model.

Identified metabolite	w* [CI]	p-value	q-value
Threonic acid	−0.185 [−0.259– −0.11]	0.0009*	0.0002
Cholesterol	−0.099 [−0.194– −0.003]	0.0898	0.0058
Campesterol	−0.092 [−0.134– −0.05]	0.1165	0.0070
D(-)Quinic acid	−0.082 [−0.138– −0.026]	0.1469	0.0084
β-Sitosterol	−0.053 [−0.098– −0.008]	0.3672	0.0191

Metabolites have w*cross-validated confidence intervals (95%) not including 0. * = Significant change from CWP p > 0.05 (one-way ANOVA). No metabolites are significantly (one-way ANOVA) different between after false discovery rate correction i.e. have a p-value < q-value. Metabolites are sorted with the most negative w* on top, i.e. the most closely associated with CON in the OPLS-DA model.

^aThe q-value for each individual ANOVA is the minimal level at which the p-value of that ANOVA may be considered significant⁶⁰.