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Penicillin susceptibility among (a) all isolates and (b) invasive pneumococcal disease (IPD)-related isolates (upper) and non-IPD isolates (lower). Panel (a) is expressed in accumulated percentages using the respective annual total isolate number as the denominator. (S, susceptible, ≤0.06 mg/L; RS, reduced susceptible, 0.06-2 mg/L; NS, non-susceptible, >2 mg/L) (Other serotypes are as those listed in Fig. 2).
