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. 2015 Apr 8;5(3):201–209. doi: 10.1016/j.apsb.2015.03.013

Scheme 2.

Scheme 2

Synthetic route for target compounds 4144. Reagents and conditions: (a) anilines, DIC, HOBt, r.t.; (b) CH3CH2COCl, TEA, r.t.; (c) CH3I, K2CO3, 50 °C.