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. 2015 Apr 10;123(11):1138–1144. doi: 10.1289/ehp.1408663

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Effects of arsenic on the oral glucose tolerance test (OGTT; A) and the insulin tolerance test (ITT; B) in female mice with or without ovariectomy. Mice were treated with D.D. water or with As₂O₃ (As) 0.05 ppm (a) or 0.5 ppm (b) in drinking water in the presence or absence of 17β-estradiol (E₂; 10 μg/kg) for 6 weeks. Data are mean ± SEM (n = 6/group). *p < 0.05 vs. sham D.D. water. ^#p < 0.05 vs. OVX D.D. water. ^$p < 0.05 vs. OVX + As₂O₃.