Table 5.
Correlations between asthma and severe RSV infection in a sample of 8,280 Danish twin pairs, 3–9 years of age
| Parent-reported asthma | Hospital-diagnosed asthma | Antigen-verified RSV | Hospital-diagnosed RSV | |
|---|---|---|---|---|
| All twins | ||||
| Parent-reported asthma | 1 | |||
| Hospital-diagnosed asthma | 0.72 | 1 | ||
| Antigen-verified RSV | 0.34 | 0.42 | 1 | |
| Hospital-diagnosed RSV | 0.32 | 0.40 | 0.93 | 1 |
| MZ twin pairs | ||||
| Parent-reported asthma | 0.95 | |||
| Hospital-diagnosed asthma | 0.57 | 0.81 | ||
| Antigen-verified RSV | 0.32 | 0.41 | 0.77 | |
| Hospital-diagnosed RSV | 0.33 | 0.48 | 0.79 | 0.93 |
| DZ twin pairs | ||||
| Parent-reported asthma | 0.62 | |||
| Hospital-diagnosed asthma | 0.31 | 0.51 | ||
| Antigen-verified RSV | 0.18 | 0.21 | 0.76 | |
| Hospital-diagnosed RSV | 0.17 | 0.25 | 0.70 | 0.84 |
Correlations for all twins denote phenotypic (within-individual) correlations, whereas correlations for MZ and DZ twin pairs denote cross-twin correlations. All correlations are statistically significant (p<0.001). Modified from [VII].